Aryl ethers and uses thereof

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO RE49948
SERIAL NO

17592108

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Abstract

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The present disclosure relates to HIF-2α inhibitors and methods of making and using them for treating cancer. Certain compounds were potent in HIF-2α scintillation proximity assay, luciferase assay, and VEGF ELISA assay, and led to tumor size reduction and regression in 786-O xenograft bearing mice in vivo.

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Patent Owner(s)

  • PELOTON THERAPEUTICS, INC.

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dixon, Darryl David Somerset, US 12 120
Grina, Jonas Coppell, US 24 213
Josey, John A Dallas, US 32 521
Rizzi, James P Irving, US 46 1238
Schlachter, Stephen T Dallas, US 49 727
Wallace, Eli M Richardson, US 87 1060
Wang, Bin Dallas, US 1095 9516
Wehn, Paul Dallas, US 18 155
Xu, Rui Dallas, US 425 2031
Yang, Hanbiao Coppell, US 34 662

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