Bispecific binding proteins and uses thereof

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO RE49908
SERIAL NO

17364539

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Abstract

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The disclosure generally provides proteins that bind two epitopes (e.g., a first and a second epitope) and that are bivalent for binding to each of the first and second epitopes. The disclosure also provides for specific binding proteins, including antibodies, which bind to a target protein. The disclosure also provides compositions comprising such proteins, nucleic acid molecules encoding such proteins and methods of making such proteins. The disclosure provides methods of inducing an immune response in a subject as well as methods for treating or preventing cancer in a subject by administering the proteins, nucleic acid molecules and/or compositions to the subject.

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Patent Owner(s)

Patent OwnerAddress
MEDIMMUNE LLCONE MEDIMMUNE WAY GAITHERSBURG MD 20878

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Carlesso, Gianluca Gaithersburg, US 16 194
Dobson, Claire Louise Cambridge, GB 14 79
Dovedi, Simon Cambridge, GB 12 24
Drabic, Stacey Gaithersburg, US 15 31
Gao, Changshou Gaithersburg, US 58 799
Hammond, Scott A Gaithersburg, US 15 214
Herbst, Ronald Gaithersburg, US 30 89
Kasturirangan, Srinath Gaithersburg, US 20 74
Lobo, Brian Gaithersburg, US 18 42
Manikwar, Prakash Gaithersburg, US 10 10
Mazor, Yariv Gaithersburg, US 23 98
Morrow, Michelle Cambridge, GB 14 359
Oberst, Michael Gaithersburg, US 13 113
Pollizzi, Kristen Gaithersburg, US 6 8
Rainey, Godfrey Gaithersburg, US 13 43
Schofield, Darren Cambridge, GB 20 14
Seaman, Jonathan Cambridge, GB 9 15

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