Variants of C-type natriuretic peptide

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United States of America Patent

PATENT NO RE48267
SERIAL NO

15646822

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Abstract

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The present disclosure provides variants of C-type natriuretic peptide (CNP), pharmaceutical compositions comprising CNP variants, and methods of making CNP variants. The CNP variants are useful as therapeutic agents for the treatment of diseases responsive to CNP, including but not limited to bone-related disorders, such as skeletal dysplasias (e.g., achondroplasia), and vascular smooth muscle disorders (e.g., restenosis and arteriosclerosis).

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Patent Owner(s)

Patent OwnerAddress
BIOMARIN PHARMACEUTICAL INC105 DIGITAL DRIVE NOVATO CA 94949

International Classification(s)

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  • 2017 Application Filing Year
  • A61K Class
  • 21227 Applications Filed
  • 12841 Patents Issued To-Date
  • 60.50 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances2017201820192020202120222023202420250255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Aoyagi-Scharber, Mika Novato, US 16 123
Castillo, Sianna Novato, US 12 211
Long, Shinong Novato, US 15 117
Okhamafe, Augustus O Concord, US 42 353
Price, Christopher P Munich, DE 17 101
Vellard, Michel Claude Novato, US 22 271
Wendt, Daniel J Novato, US 33 436

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  • 1 Citation Count
  • A61K Class
  • 66.68 % this patent is cited more than
  • 5 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges13636645326377163101 - 1011 - 2021 - 3031 - 4041 - 5051 - 600100020003000400050006000700080009000100001100012000130001400015000

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