Amide-substituted heterocyclic compounds useful as modulators of IL-12, IL-23 and/or IFNα responses

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United States of America

PATENT NO RE47929
SERIAL NO

16201653

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Abstract

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Compounds having the following formula I: or a stereoisomer or pharmaceutically-acceptable salt thereof, where R1, R2, R3, R4, and R5 are as defined herein, are useful in the modulation of IL-12, IL-23 and/or IFNα, by acting on Tyk-2 to cause signal transduction inhibition.

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BRISTOL-MYERS SQUIBB COMPANYROUTE 206 & PROVINCE LINE ROAD PRINCETON NJ 08543

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Lin, Shuqun Newtown, US 21 235
Moslin, Ryan M Princeton, US 23 122
Spergel, Steven H Warrington, US 52 543
Tokarski, John S Princeton, US 45 497
Weinstein, David S San Diego, US 38 190
Wrobleski, Stephen T Flemington, US 59 788
Zhang, Yanlei Princeton, US 15 94

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