Compounds for treating spinal muscular atrophy

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United States of America Patent

PATENT NO RE47689
SERIAL NO

15695299

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Abstract

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Provided herein are compounds, compositions thereof and uses therewith for treating spinal muscular atrophy. In a specific embodiment, provided herein are compounds of a form that may be used to modulate the inclusion of exon 7 of SMN2 into mRNA that is transcribed from the SMN2 gene. In another specific embodiment, provided herein are compounds of a form that may be used to modulate the inclusion of exon 7 of SMN1 into mRNA that is transcribed from the SMN1 gene. In yet another embodiment, provided herein are compounds of a form that may be used to modulate the inclusion of exon 7 of SMN1 and SMN2 into mRNA that is transcribed from the SMN1 and SMN2 genes, respectively.

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Patent Owner(s)

Patent OwnerAddress
PTC THERAPEUTICS INCSOUTH PLAINFIELD NJ 07080

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Guangming Bridgewater, US 58 1013
Choi, Soongyu New York, US 47 562
Dakka, Amal Whitehouse Station, US 21 150
Huang, Song San Leandro, US 36 743
Karp, Gary Mitchell Princeton Junction, US 67 983
Lee, Chang-Sun Belle Mead, US 17 138
Li, Chunshi East Brunswick, US 12 185
Narasimhan, Jana Scotch Plains, US 32 143
Naryshkin, Nikolai East Brunswick, US 26 242
Paushkin, Sergey Belle Mead, US 4 48
Pinard, Emmanuel Linsdort, FR 113 721
Qi, Hongyan Plainsboro, US 28 344
Ratni, Hasane Habsheim, FR 131 514
Turpoff, Anthony A Hillsborough, US 13 191
Weetall, Marla L Morristown, US 33 238
Welch, Ellen Califon, US 37 313
Woll, Matthew G Dunellen, US 25 116
Yang, Tianle Mountainside, US 39 448
Zhang, Nanjing Princeton, US 32 135
Zhang, Xiaoyan Belle Mead, US 147 1153
Zhao, Xin Belle Mead, US 1071 7724

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