Recombinant cell clones having increased stability and methods of making and using the same
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United States of America Patent
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Mar 6, 2018
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Dec 11, 2014
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Jun 20, 1997
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Abstract
Disclosed are a stable recombinant cell clones which are stable in serum- and protein-free medium for at least 40 generations, a biomass obtained by multiplying the stable cell clone under serum- and protein-free culturing conditions, and a method of preparing recombinant proteins by means of the biomass. Furthermore, the invention relates to a method of recovering stable recombinant cell clones.
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