Heterobifunctional pan-selectin inhibitors
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United States of America Patent
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Feb 25, 2014
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N/A
app pub date -
May 30, 2012
filing date -
Sep 2, 2005
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Abstract
Compounds and methods are provided for modulating in vitro and in vivo processes mediated by selectin binding. More specifically, selectin modulators and their use are described, wherein the selectin modulators that modulate (e.g., inhibit or enhance) a selectin-mediated function comprise particular glycomimetics alone or linked to a member of a class of compounds termed BASAs (Benzyl Amino Sulfonic Acids) or a member of a class of compounds termed BACAs (Benzyl Amino Carboxylic Acids).
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