Cells expressing pluripotency markers and expressing markers characteristic of the definitive endoderm
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United States of America Patent
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Dec 25, 2012
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Feb 14, 2012
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Apr 24, 2008
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Abstract
The present invention is directed to pluripotent cells that can be readily expanded in culture on tissue culture substrate that is not pre-treated with protein or an extracellular matrix, and do not require a feeder cell line. The present invention also provides methods to derive the pluripotent cell line from human embryonic stem cells.
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