Methods for the preparation, isolation and purification of epothilone B, and X-ray crystal structures of epothilone B
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United States of America Patent
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Mar 1, 2011
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app pub date -
Aug 6, 2009
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Sep 23, 2002
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Abstract
The present invention relates to improved methods for the production, isolation and purification of epothilone B. These methods include, for example, a fermentation process for the production of epothilone B, isolation via adsorption onto a resin, and subsequent purification.
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