Pharmaceutical composition containing a stable modification of torasemide
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United States of America
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Jul 26, 1994
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N/A
app pub date -
Apr 8, 1993
filing date -
Aug 17, 1985
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Abstract
The present invention provides a process for the preparation of cystalline torasemide in the pure modification I (monoclinic, space group P2.sub.1 /c, melting point 162.degree. C.) from torasemide of modification II (monoclinic, space group P2/n, melting point 169.degree. C.), wherein a suspension of torasemide of modification II is stirred in water with the addition of a catalytic amount of modification I until the rearrangement is complete. The present invention also provides pharmaceutical compositions containing torasemide of modification I.
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