Process for the preparation of 7.alpha.-methoxy-7.beta.-(1,3-diethietane-2-carboxyamido)cephalosporanic acid derivatives
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United States of America
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Sep 1, 1987
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app pub date -
Apr 25, 1985
filing date -
Jun 10, 1977
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Abstract
The invention relates to novel 7.alpha.-methoxycephalosporin derivatives having at the 7.beta.-position an amido group acylated by a 1,3-dithietane carboxylic acid residue and to 7.beta.-isothiazolylthioacetamido-7.alpha.-methoxycephalosporins having antibacterial activity by themselves and, as the case may be, capable of being converted into the aforesaid 7.alpha.-methoxycephalosporin derivatives. The compounds of this invention exhibit excellent antibacterial activity and are particularly effective against gram negative bacteria.
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