Products comprising an extracellular matrix tissue material and osteogenic protein

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United States of America Patent

PATENT NO 9993580
SERIAL NO

15058329

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Abstract

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Osteogenic compositions include a decellularized extracellular matrix tissue and bone morphogenic protein, preferably BMP-2. The compositions make beneficial use of the BMP, which can be used at relatively low doses and can bind to native components (e.g., native sulfated glycosaminoglycans such as heparin and/or heparan sulfate) remaining in the decellularized extracellular matrix tissue. Methods for preparation and use of such compositions are also described. The compositions and related methods can be used in the treatment of diseased or damaged bone tissue.

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Patent Owner(s)

Patent OwnerAddress
MUFFIN INCORPORATED1400 CUMBERLAND AVENUE WEST LAFAYETTE IN 47906

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Charlebois, Steven West Lafayette, US 22 187
Fearnot, Neal E West Lafayette, US 153 17800
Scoville, Shelley Lynn Athens, US 1 0
Steinhart, Christine M Ramona, US 3 3
Taylor, Amanda F West Lafayette, US 4 3

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