Human monoclonal antibodies to O8E

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United States of America Patent

PATENT NO 9988453
APP PUB NO 20160168249A1
SERIAL NO

15048785

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present disclosure provides isolated monoclonal antibodies, particularly human monoclonal antibodies that specifically bind to O8E with high affinity. Nucleic acid molecules encoding the antibodies of this disclosure, expression vectors, host cells and methods for expressing the antibodies of this disclosure are also provided. Immunoconjugates, bispecific molecules and pharmaceutical compositions comprising the antibodies of this disclosure are also provided. This disclosure also provides methods for treating cancer.

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Patent Owner(s)

Patent OwnerAddress
E R SQUIBB & SONS L L CPRINCETON NJ 08540

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Huang, Haichun Fremont, US 121 4072
Korman, Alan J Piedmont, US 132 5349
Lu, Li-Sheng Mountain View, US 12 205
Selby, Mark J San Francisco, US 100 4018
Witte, Alison J Scotts Valley, US 4 11

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