Dendritic cell marker and uses thereof

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United States of America Patent

PATENT NO 9988431
SERIAL NO

13848503

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Abstract

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The present invention relates to the identification of proteins located on the cell surface of dendritic cells or precursors thereof, particularly antigen presenting dendritic cells. In particular, the present invention relates to compounds such as antibodies that bind these proteins. These compounds can be used to detect and/or enrich a subset of dendritic cells or precursors thereof. These compounds can also be used to target antigens to dendritic cells or precursors thereof to modulate a humoral and/or T cell mediated immune response to an antigen, or used to target cytotoxic agents to dendritic cells or precursors thereof involved in diseased states.

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Patent Owner(s)

Patent OwnerAddress
THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH1G ROYAL PARADE PARKVILLE MELBOURNE VICTORIA 3052 AUSTRALIA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Caminschi, Irina Ascot Vale, AU 7 55
Lahoud, Mireille Hanna East Melbourne, AU 7 55
Lew, Andrew Mark Essendon, AU 8 26
Proietto, Anna Irene Bulleen, AU 2 1
Shortman, Ken Princess Hill, AU 7 28
Wright, Mark Dexter Northcote, AU 6 55
Wu, Li Ascot Vale, AU 56 529

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