Compositions and methods of using chondroitinase ABCI mutants
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United States of America Patent
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Jun 5, 2018
Issued Date -
Feb 2, 2017
app pub date -
Aug 5, 2016
filing date -
Oct 10, 2006
priority date (Note) -
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Abstract
The present disclosure relates to protein and nucleic acid mutants of chondroitinase ABCI. Such nucleic acid mutants encode for chondroitinase ABCI mutant enzymes exhibiting altered chondroitin lyase activity or increased resistance to inactivation from stressors including UV light or heat. Methods of using such nucleic acid mutants encoding chondroitinase ABCI mutant enzymes is also provided.
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International Classification(s)
- C07H:SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTI....
- A61K:PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOS....
- C12P:FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESI....
- C12N:MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF
- C07K:PEPTIDES
- A61M:DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE B....
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