Modified gram positive bacteria and uses thereof
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United States of America Patent
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May 29, 2018
Issued Date -
N/A
app pub date -
Jan 21, 2016
filing date -
Sep 23, 2011
priority date (Note) -
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Abstract
The present invention relates to gram positive bacteria with increased stress resistance and/or improved storage characteristics. In particular, the invention relates to gram positive bacterium which accumulate intracellular trehalose. The gram positive bacterium according to the invention lack cellobiose-specific PTS system IIC component (PtcC) activity. The gram positive bacterium may further lack trehalose 6-phosphate phosphorylase (TrePP) activity. The gram positive bacterium may further overexpress trehalose transporters. The invention further relates to compositions comprising such gram positive bacterium as well as methods and uses thereof.
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International Classification(s)
- A61K:PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOS....
- C12R:INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C-C1....
- C12P:FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESI....
- A23L:FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT....
- C12N:MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF
- A23K:FODDER
- C07K:PEPTIDES
- A23C:DAIRY PRODUCTS, e.g. MILK, BUTTER, CHEESE; MILK OR....
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