KDM1A inhibitors for the treatment of disease

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United States of America Patent

PATENT NO 9981922
SERIAL NO

15043121

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Abstract

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Disclosed herein are new compounds and compositions and their application as pharmaceuticals for the treatment of diseases. Methods of inhibition of KDM1A, methods of increasing gamma globin gene expression, and methods to induce differentiation of cancer cells in a human or animal subject are also provided for the treatment of diseases such as acute myelogenous leukemia.

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Patent Owner(s)

  • IMAGO BIOSCIENCES, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Celatka, Cassandra Hull, US 25 135
Clare, Michael Skokie, US 96 925
McCall, John M Boca Grande, US 93 846
Rienhoff,, Jr Hugh Y San Carlos, US 22 153
Tapper, Amy E Boston, US 15 102

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