Isolation and purification of anti-IL-13 antibodies using protein A affinity chromatography
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United States of America Patent
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May 22, 2018
Issued Date -
N/A
app pub date -
Jan 19, 2016
filing date -
Oct 20, 2009
priority date (Note) -
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Abstract
Disclosed herein are methods for the isolation and purification of anti-IL-13 antibodies wherein the use of an affinity chromatographic step results in an antibody composition sufficiently pure for pharmaceutical uses. The methods described herein comprise pH viral reduction/inactivation, ultrafiltration/diafiltration, affinity chromatography (e.g., Protein A affinity chromatography), ion exchange chromatography, and hydrophobic chromatography. Further, the present invention is directed toward pharmaceutical compositions comprising one or more antibodies of the present invention.
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Cited Art Landscape
Patent Citation Ranking
- 7 Citation Count
- A61K Class
- 50.93 % this patent is cited more than
- 7 Age
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