Composition of novel carbohydrate drug for treatment of human diseases
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United States of America Patent
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May 22, 2018
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Apr 4, 2017
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Dec 28, 2011
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Abstract
Aspects of the invention provide compositions for use in the treatment galectin-dependent diseases. In particular, compositions comprising a selectively depolymerized, branched galactoarabino-rhamnogalacturonate whose backbone is predominantly comprised of 1,4-linked galacturonic acid (GalA) moieties, with a lesser backbone composition of alternating 1,4-linked GalA and 1,2-linked rhamnose (Rha), which in-turn is linked to any number of side chains, including predominantly 1,4-b-D-galactose (Gal) and 1,5-α-L-arabinose (Ara) residues.
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