Stabilisation of radiopharmaceutical precursors

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United States of America Patent

PATENT NO 9969761
SERIAL NO

14258247

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Abstract

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The present invention relates to a method for improving stability of non fluoridated sugar derivatives, and in particular glucose derivatives such as 1,3,4,6-tetra-O-acetyl-2-O-trifluoromethanesulfonyl-β-D-mannopyranose which are used as precursors for production of radiofluoridated sugar derivatives for use in in vivo imaging procedures such as positron emission tomography (PET). The method comprises storing the non fluoridated sugar derivative in an organic solvent. The resultant formulations of the non fluoridated sugar derivative and cassettes for automated synthesis apparatus comprising the same are also claimed.

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Patent Owner(s)

Patent OwnerAddress
GE HEALTHCARE AS0485 OSLO
GE HEALTHCARE LIMITEDCHALFONT ST GILES BUCKINGHAMSHIRE HP8 4SP

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Grigg, Julian Amersham, GB 28 81
In't, Veld Dirk-Jan Oslo, NO 2 0
Osborn, Nigel John Amersham, GB 7 19
Wickstrom, Torild Oslo, NO 12 9
Wilson, Anthony Waddesdon, GB 20 422

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