Deglycosylation reagents and methods
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United States of America Patent
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May 8, 2018
Issued Date -
N/A
app pub date -
Dec 28, 2016
filing date -
May 30, 2014
priority date (Note) -
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status (Latency Note)
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Abstract
Compositions and methods are provided for efficiently preparing a completely deglycosylated antibody where efficiency is measured in relative amounts of reagents in soluble or lyophilized form, and time and temperature of the reaction. Compositions and methods are also provided for separating substantially all N-linked glycans from a glycosylated antibody and for preserving functionality of the antibody. The methods are compatible with glycan labeling and protease digestion without the need for prior purification steps.
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Cited Art Landscape
Patent Citation Ranking
- 2 Citation Count
- C12N Class
- 58.13 % this patent is cited more than
- 7 Age
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