Compositions and methods of use
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United States of America Patent
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May 8, 2018
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app pub date -
Apr 29, 2013
filing date -
Apr 27, 2012
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Abstract
The present invention relates to a derivative bacterial strain of an avirulent, non-pathogenic Clostridium ghonii that is capable of arresting the growth of, regressing or destroying one or more solid tumors. The present invention further relates to a composition comprising the derivative bacterial strain for targeted lysis of solid tumors. The present invention further relates to methods of producing derivative strains of C. ghonii by serial culturing in tumor bearing animals.
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