Genetically engineered bacterium for the production of 3-hydroxybutyrate

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United States of America Patent

PATENT NO 9957531
SERIAL NO

15658668

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Abstract

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The invention relates to a genetically engineered bacterium having an enzyme that converts acetyl-CoA to acetoacetyl-CoA, an enzyme that converts acetoacetyl-CoA to 3-hydroxybutyryl-CoA, and an enzyme that converts 3-hydroxybutyryl-CoA to 3-hydroxybutyrate. The bacterium may also have enzymes to produce other downstream products, such as 3-hydroxybutyryaldehyde, and 1,3-butanediol. Typically, the bacterium is capable of producing these products from a gaseous substrate, such as syngas or an industrial waste gas.

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Patent Owner(s)

  • LANZATECH NEW ZEALAND LIMITED

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Behrendorff, James Bruce Yarnton Haycock Copenhagen, DK 7 29
Hill, Ryan Edward Stockholm, SE 11 30
Jensen, Rasmus Overgaard Skokie, US 7 19
Juminaga, Darmawi Skokie, US 4 2
Koepke, Michael Skokie, US 79 227
Mueller, Alexander Paul Skokie, US 13 39

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