Method for enzymatic treatment of tissue products

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United States of America Patent

PATENT NO 9957477
SERIAL NO

14962125

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Abstract

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Methods for treating tissue matrices and tissue matrices produced according to the methods are provided. The methods can include treating a tissue matrix with a proteolytic enzyme to produce a desired pliability of the tissue matrix and/or to control the immunogenicity of the tissue matrix. The methods can also comprise performing an assay to determine if contacting the at least one collagen-containing tissue matrix with a proteolytic enzyme has altered the at least one collagen-containing tissue matrix to reduce a human immune response to the tissue matrix.

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Patent Owner(s)

Patent OwnerAddress
LIFECELL CORPORATION1N WAUKEGAN ROAD NORTH CHICAGO IL 60064

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Yi Lawrenceville, US 458 3558
Huang, Li Ting Branchburg, US 18 79
Sun, Wenquan Warrington, US 40 449
Wan, Hua Princeton, US 25 140
Xu, Hui Plainsboro, US 440 2426

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