Method for preparing multilayer lamellar liquid crystal emulsion including intercellular lipids
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United States of America Patent
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Apr 24, 2018
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Sep 27, 2013
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Sep 26, 2013
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Abstract
A method for preparing a liquid crystal emulsion includes: a) mixing, warming and dissolving intercellular lipid ingredients, non-polyoxyethylene (POE) based non-ionic surfactant, higher fatty alcohol, oil and wax to provide an oil phase part; b) mixing, warming and dissolving water, polyol and the other aqueous phase ingredients to provide an aqueous phase part; c) adding the oil phase part to the aqueous phase part, followed by agitation; d) introducing a viscosity modifier to the mixture solution under agitation; e) subjecting the mixture solution to rapid cooling under vacuum while carrying out debubbling under vacuum; and f) filtering the mixture solution through a filtering paper or filtering cloth. Provided is a stable liquid crystal emulsion having a multilayer lamellar structure including a large amount of intercellular lipid ingredients through a process using rapid cooling. The liquid crystal emulsion has an oil phase part and an aqueous phase part.
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