Methods for identifying modulators of Ras using nonlinear techniques
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United States of America Patent
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Apr 10, 2018
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Nov 2, 2012
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Feb 5, 2012
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Abstract
Provided herein are compositions and methods for identifying and detecting modulators of Ras protein conformational states through the use of second harmonic generation (SHG) technology. Also provided herein are methods for detecting a conformational changes in the three dimensional structure of a protein bound to a supported lipid bilayer.
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