Non-natural amino acid tRNA synthetases for para-methylazido-L-phenylalanine

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United States of America Patent

PATENT NO 9938516
SERIAL NO

15028396

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Abstract

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The invention provides methods and compositions for a mutein aminoacyl-tRNA synthetase that preferentially charges a tRNA with a non-natural amino acid. Also provided are methods for incorporating the non-natural amino acid, para-methylazido-L-phenylalanine into a protein and further conjugating a biologically active adduct to the para-methylazido-L-phenylalanine.

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Patent Owner(s)

Patent OwnerAddress
SUTRO BIOPHARMA INC111 OYSTER POINT BLVD SOUTH SAN FRANCISCO CA 94080

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Thanos, Christopher Tiburon, US 46 493
Zimmerman, Erik S Pacifica, US 5 29

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  • 9 Citation Count
  • A61K Class
  • 50.93 % this patent is cited more than
  • 7 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges92918022655157761477225301 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +050010001500200025003000350040004500500055006000650070007500800085009000950010000

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