Production of near monodisperse particles using milling and membrane separation
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United States of America Patent
Stats
-
Apr 10, 2018
Issued Date -
N/A
app pub date -
Mar 28, 2013
filing date -
Mar 30, 2012
priority date (Note) -
In Force
status (Latency Note)
Importance
Abstract
The present invention provides a method for producing particles having a reduced particle size distribution, which method comprises the steps of: a) providing a composition comprising particles; b) subjecting the particles in said composition to a size reduction step or to a size growth step; c) feeding said particles to a first membrane separation system to separate said particles according to size; d) recycling those particles that do not meet the size criteria back to step a); e) optionally, collecting in a collection tank the permeate of the first membrane separation system. Particles obtainable according to the method of the invention and characterized by having a near monodisperse particle size distribution are also provided. The particles are preferably characterized by having a particle size distribution with a span of less than 2.0. The invention also provides pharmaceutical compositions comprising particles according to the invention, and also apparatus for carrying out the method of the invention.
First Claim
Other Claims data not available
Family
International Classification(s)
- A61K:PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOS....
- B02C:CRUSHING, PULVERISING, OR DISINTEGRATING IN GENERA....
- B03B:SEPARATING SOLID MATERIALS USING LIQUIDS OR USING ....
- B07B:SEPARATING SOLIDS FROM SOLIDS BY SIEVING, SCREENIN....
- B01J:CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS, CO....
- B01D:SEPARATION
- 2013 Application Filing Year
- A61K Class
- 12711 Applications Filed
- 11051 Patents Issued To-Date
- 86.95 % Issued To-Date
Cited Art Landscape
Patent Citation Ranking
- 0 Citation Count
- A61K Class
- 0 % this patent is cited more than
- 7 Age
Maintenance Fees
| Fee | Large entity fee | small entity fee | micro entity fee | due date |
|---|---|---|---|---|
| 7.5 Year Payment | $3600.00 | $1800.00 | $900.00 | Oct 10, 2025 |
| 11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | Oct 10, 2029 |
