High throughput screening of crystallization of materials
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United States of America Patent
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Apr 3, 2018
Issued Date -
N/A
app pub date -
Oct 9, 2015
filing date -
Jun 27, 2000
priority date (Note) -
In Force
status (Latency Note)
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Abstract
High throughput screening of crystallization of a target material is accomplished by simultaneously introducing a solution of the target material into a plurality of chambers of a microfabricated fluidic device. The microfabricated fluidic device is then manipulated to vary the solution condition in the chambers, thereby simultaneously providing a large number of crystallization environments. Control over changed solution conditions may result from a variety of techniques, including but not limited to metering volumes of crystallizing agent into the chamber by volume exclusion, by entrapment of volumes of crystallizing agent determined by the dimensions of the microfabricated structure, or by cross-channel injection of sample and crystallizing agent into an array of junctions defined by intersecting orthogonal flow channels.
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| Fee | Large entity fee | small entity fee | micro entity fee | due date |
|---|---|---|---|---|
| 7.5 Year Payment | $3600.00 | $1800.00 | $900.00 | Oct 3, 2025 |
| 11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | Oct 3, 2029 |
