Modulators for Sirt5 and assays for screening same

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United States of America Patent

PATENT NO 9932621
SERIAL NO

13808706

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Abstract

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Sirt5, a mitochondrial Sirtuin, has been identified herein as an efficient demalonylase and desuccinylase. Disclosed herein are assays to identify Sirt5 modulators based on this robust enzymatic activity. Sirt5-specific modulators can be used study the biological function of Sirt5 and to target Sirt5 activities in treating human diseases.

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Patent Owner(s)

Patent OwnerAddress
CORNELL UNIVERSITYCORNELL CENTER FOR TECHNOLOGY ENTERPRISE & COMMERCIALIZATION ("CCTEC") 395 PINE TREE ROAD SUITE 310 ITHACA NY 14850

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Lin, Hening New York, US 13 6

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