Signal amplification in lateral flow and related immunoassays
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United States of America Patent
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Mar 20, 2018
Grant Date -
Oct 15, 2015
app pub date -
Apr 16, 2015
filing date -
Nov 21, 2011
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Abstract
The present invention provides methods, devices, compositions (e.g., capture complexes), and kits useful for enhancing the detection of antibodies in a test sample. The methods, devices, and compositions utilize detectable Fc-binding molecules such as Protein A, Protein G, and/or an Fc-specific antibody to amplify the signal of a detected antibody in immunoassays, such as lateral flow assays.
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