Compositions and their uses directed to huntingtin

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United States of America Patent

PATENT NO 9920321
APP PUB NO 20160369273A1
SERIAL NO

15142827

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Disclosed herein are compounds, compositions and methods for modulating the expression of huntingtin in a cell, tissue or animal. Further provided are methods of slowing or preventing Huntington's Disease (HD) progression using an antisense compound targeted to huntingtin. Additionally provided are methods of delaying or preventing the onset of Huntington's Disease (HD) in an individual susceptible to Huntington's Disease (HD). Also provided are uses of disclosed compounds and compositions in the manufacture of a medicament for treatment of diseases and disorders.

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Patent Owner(s)

Patent OwnerAddress
IONIS PHARMACEUTICALS INCCALIFORNIA USA CALIFORNIA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Freier, Susan M San Diego, US 526 6555

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