Methods of producing immunoconjugates

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United States of America Patent

PATENT NO 9920124
SERIAL NO

14654384

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides methods of preparing active immunoconjugates, including anti-CD22 immunoconjugates. Suitably, the methods include a fed-batch refolding process and/or column stripping process that result in an increase in yield of the immunoconjugate over other processes that do not utilize the methods.

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Patent Owner(s)

Patent OwnerAddress
MEDIMMUNE LIMITEDCAMBRIDGE CAMBRIDGESHIRE CB21 6GH

International Classification(s)

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  • 2013 Application Filing Year
  • A61K Class
  • 12711 Applications Filed
  • 11051 Patents Issued To-Date
  • 86.95 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances2013201420152016201720182019202020212022202320240255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fulton, Andrew Gaithersburg, US 1 0
Hunter, Alan Gaithersburg, US 15 36
Linke, Thomas Gaithersburg, US 17 43
Pabst, Timothy Gaithersburg, US 6 6
Thompson, Christopher Gaithersburg, US 116 2643
Wang, Xiangyang Gaithersburg, US 33 29
Wendeler, Michaela Gaithersburg, US 2 1
Xi, Guoling Gaithersburg, US 2 0

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  • 0 Citation Count
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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges92918022655157761477225301 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +050010001500200025003000350040004500500055006000650070007500800085009000950010000

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