Preparation of recombinant human plasma phospholipid transfer protein (PLTP) from the milk of transgenic rabbits
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United States of America Patent
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Mar 20, 2018
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Aug 8, 2013
app pub date -
Apr 6, 2011
filing date -
Apr 9, 2010
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Abstract
The invention relates to obtaining a preparation of recombinant human PLTP from the milk of a transgenic animal containing in its genome one or more copies of a transgene comprising a polynucleotide coding for human PTLP, placed under transcriptional control of a promoter permitting its specific expression in the cells of the mammary glands of said animal. The recombinant human PLTP preparation obtained can be used in the prevention or treatment of septic shock.
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