Mimotopes of tropomyosin for use in immunotherapy for shellfish and/or arthropod allergy
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United States of America Patent
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Mar 20, 2018
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Jun 3, 2016
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Jun 5, 2015
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Abstract
The present invention provides isolated peptides and nucleic acids encoding the isolated peptides that can modify a subject's immune response to tropomyosin. The isolated peptides correspond to peptide epitope mimics that are based on an invertebrate tropomyosin allergen, e.g., the shrimp tropomyosin Met e 1. Also provided are compositions and methods of use thereof to reduce, minimize or eliminate an allergic response to arthropods and/or shellfish.
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