Co-precipitation of a therapeutic agent into hydroxyapatite coatings

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United States of America Patent

PATENT NO 9919077
APP PUB NO 20160144070A1
SERIAL NO

14897352

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Abstract

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A method for co-precipitating a therapeutic agent into a hydroxyapatite coated surface includes the steps of providing a surface and applying a hydroxyapatite seed layer on the surface. The hydroxyapatite seed layered surface is contacted with a solution including the therapeutic agent and a co-precipitated therapeutic agent, hydroxyapatite layer is formed on the coated surface to uniformly distribute the therapeutic agent in the layer. Further, an implant having sustained therapeutic agent delivery includes a base and an hydroxyapatite seed layer disposed on a surface of the base. A co-precipitated hydroxyapatite coating is disposed on the seed layer. The coating includes a therapeutic agent, wherein the therapeutic agent is provided in a solution of therapeutic agent.

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Patent Owner(s)

Patent OwnerAddress
STRYKER EUROPEAN OPERATIONS HOLDINGS LLC2825 AIRVIEW BOULEVARD KALAMAZOO MI 49002

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Lilja, Mirjam Farsta, SE 7 178
Procter, Philip Divonne les Bains, FR 16 583
Sörensen, Torben Christian Mönkeberg, DE 5 182
Soerensen, Jan Kiel, DE 4 29
Steckel, Hartwig Kiel, DE 14 195

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