Process for detection of DNA modifications and protein binding by a single molecule manipulation

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United States of America Patent

PATENT NO 9915655
SERIAL NO

14761944

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Abstract

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The present invention relates to a method for determining whether a protein binds to a specific DNA sequence. This method is useful in particular for identifying modifications to the DNA sequence (e.g. methylations) via the binding of proteins that specifically recognize those modifications (e.g. antibodies), but also to identify the binding sequence on DNA of a variety of proteins.

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Patent Owner(s)

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SORBONNE UNIVERSITE21 RUE DE L'ÉCOLE DE MÉDECINE PARIS 75006

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Allemand, Jean-Francois Bourg la Reine, FR 5 18
Bensimon, David Paris, FR 29 377
Croquette, Vincent Antony, FR 16 81
Ding, Fang-Yuan Alhambra, US 6 29
Gouet, Harold Paris, FR 1 14

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