Dimeric bacteriophage lysins
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United States of America Patent
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Mar 13, 2018
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N/A
app pub date -
Jan 27, 2016
filing date -
Oct 5, 2011
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Abstract
The present invention provides isolated dimeric Streptococcus-specific phage lysins having two Streptococcus-specific phage lysin monomers covalently linked to each other, and having killing activity against one or more Streptococcus bacteria. Also provided for are pharmaceutical compositions of dimeric lysins and their use in therapeutic treatment or alleviation of infections or bacterial colonizations. The dimeric lysins may also be used to decontaminate porous and non-porous surfaces or devices.
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