bacteriophage lysins for detection and treatment of gram positive bacteria

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United States of America Patent

PATENT NO 9914915
SERIAL NO

14685696

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Abstract

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The present invention provides methods, compositions and articles of manufacture useful for the prophylactic and therapeutic amelioration and treatment of gram-positive bacteria, including Streptococcus and Staphylococcus, and related conditions. The invention provides compositions and methods incorporating and utilizing Streptococcus suis derived bacteriophage lysins, particularly PlySs2 and/or PlySs1 lytic enzymes and variants thereof, including truncations thereof. Methods for treatment of humans are provided.

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Patent Owner(s)

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THE ROCKEFELLER UNIVERSITY1230 YORK AVENUE NEW YORK NY 10065

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Euler, Chad New York, US 14 31
Fischetti, Vincent A West Hempstead, US 55 806
Gilmer, Daniel New York, US 8 29
Schmitz, Jonathan New York, US 10 29

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