VEGF antagonist formulations suitable for intravitreal administration

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United States of America Patent

PATENT NO 9914763
SERIAL NO

15095606

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Ophthalmic formulations of a vascular endothelial growth factor (VEGF)-specific fusion protein antagonist are provided suitable for intravitreal administration to the eye. The ophthalmic formulations include a stable liquid formulation and a lyophilizable formulation. Preferably, the protein antagonist has an amino acid sequence of SEQ ID NO:4.

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Patent Owner(s)

Patent OwnerAddress
REGENERON PHARMACEUTICALS INC777 OLD SAW MILL RIVER RD TARRYTOWN NY 10591-6707

International Classification(s)

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  • 2016 Application Filing Year
  • A61K Class
  • 19101 Applications Filed
  • 13019 Patents Issued To-Date
  • 68.16 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances20162017201820192020202120222023202420250255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dix, Daniel LaGrangeville, US 37 1594
Frye, Kelly Mendham, US 31 1161
Furfine, Eric Concord, US 29 1148
Graham, Kenneth Pleasant Valley, US 32 789

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Patent Citation Ranking

  • 38 Citation Count
  • A61K Class
  • 99.36 % this patent is cited more than
  • 7 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges92918022655157761477225301 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +050010001500200025003000350040004500500055006000650070007500800085009000950010000

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