Methods of synthesizing a difluorolactam analog

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United States of America Patent

PATENT NO 9914725
SERIAL NO

14775591

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Abstract

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The present invention relates to processes and intermediates for preparing compounds of formula (IA), wherein R1, R4, R5, R6, and L1 are as defined herein. Compounds of formula (IA) have been found useful as EP4 receptor agonists useful in the treatment of glaucoma, osteoporosis, neuropathic pain, and related disorders.

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Patent Owner(s)

  • CAYMAN CHEMICAL COMPANY, INCORPORATED

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Barrett, Stephen Douglas Hartland, US 48 517
Colombo, Joseph Michael Ann Arbor, US 15 31
Germain, Bradlee David Ann Arbor, US 16 34
Kornilov, Andriy Ypsilanti, US 17 70
Kramer, James Bernard Sylvania, US 32 185
Uzieblo, Adam Farmington Hills, US 19 34

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