Methods and apparatus for the selection and/or processing of particles, in particular for the selective and/or optimised lysis of cells
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United States of America Patent
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Mar 13, 2018
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app pub date -
Apr 12, 2007
filing date -
Apr 12, 2006
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Abstract
Methods and apparatus for the selection or processing of particles sensitive to the application of an external stimulus, in which is produced, by applying the external stimulus, the rupture/lysis of at least one selected particle or the fusion of first and second selected particles, by means of the organization of the particles using a first field of force by selectively energizing electrodes of an array of selectable electrodes having dimensions comparable to or smaller than those of the particles, applying to the electrodes a first configuration of stresses; and by applying to the electrodes a second configuration of stresses, so as to create a second field of force, located substantially close to at least one selected particle to be lysated or to a pair of first and second particles to be fused and such as to produce the application of a stimulus suited to produce their lysis or fusion.
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