Selective cell targeting using adenovirus and chemical dimers

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United States of America Patent

PATENT NO 9913866
SERIAL NO

14485472

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Abstract

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Compositions and methods for retargeting adenovirus to a cell using chemical dimers are described. In particular, a recombinant adenovirus comprising a nucleic acid comprising a capsid-dimerizing agent binder conjugate and a ligand-dimerizing agent binder conjugate is provided.

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Patent Owner(s)

Patent OwnerAddress
SALK INSTITUTE FOR BIOLOGICAL STUDIES10010 N TORREY PINES ROAD LA JOLLA CA 92037-1002

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Miyake-Stoner, Shigeki La Jolla, US 8 46
O'Shea, Clodagh San Diego, US 29 120
Powers, Colin San Diego, US 24 141

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