Uridine diphosphate derivatives, prodrugs, compositions and uses thereof
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United States of America Patent
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Mar 13, 2018
Grant Date -
Sep 24, 2015
app pub date -
Sep 27, 2013
filing date -
Sep 28, 2012
priority date (Note) -
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Abstract
This disclosure relates to the use of uridine diphosphate (UDP) derivatives, salts and/or prodrugs thereof for the treatment of inflammatory conditions (e.g., psoriasis) and glaucoma, to prodrugs of UDP derivatives, compositions comprising therapeutically effective amounts of those prodrugs of the UDP derivatives and methods of using those prodrugs for treating various disorders including, e.g., neuronal disorders, including neurodegenerative disorders (e.g., Alzheimer's disease, Parkinson's disease) and traumatic CNS injury, pain, Down Syndrome (DS), glaucoma, and inflammatory conditions, e.g., psoriasis and rheumatoid arthritis.
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