Combination therapy with an anti-hyaluronan agent and therapeutic agent
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United States of America Patent
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Mar 13, 2018
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app pub date -
Mar 15, 2013
filing date -
Apr 4, 2012
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Abstract
Provided herein is combination therapy containing an anti-hyaluronan agent, such as a polymer-conjugated hyaluronan-degrading enzyme, and a tumor-targeted taxane, and optionally a further chemotherapeutic agent such as a nucleoside analog. The combination therapy can be used in methods of treating cancers, and in particular solid tumor cancers.
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