Compositions and methods for modulating c-Rel-dependent cytokine production

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United States of America Patent

PATENT NO 9910031
SERIAL NO

14542453

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Abstract

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The present invention is directed to compositions and methods for modulating c-Rel-dependent cytokine production without materially altering the level of expression of NFκB and/or the amount of IκB. The present invention is also directed to screening for modulators of c-Rel activity as determined by assaying for altered subcellular localization of c-Rel but where the level of expression of NFκB and/or the amount of IκB is materially unaltered.

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Patent Owner(s)

Patent OwnerAddress
MADRIGAL PHARMACEUTICALS INC200 BARR HARBOR DRIVE SUITE 200 WEST CONSHOHOCKEN PA 19428

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Barsoum, James Lexington, US 17 280
Lu, Rongzhen Lincoln, US 11 56
Wada, Yumiko Billerica, US 42 691

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