Induction of pluripotent cells
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United States of America Patent
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Mar 6, 2018
Issued Date -
N/A
app pub date -
Mar 3, 2015
filing date -
Oct 16, 2009
priority date (Note) -
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Abstract
The slow kinetics and low efficiency of reprogramming methods to generate human induced pluripotent stem cells (iPSCs) impose major limitations on their utility in biomedical applications. Here we describe a chemical approach that dramatically improves (>200 fold) the efficiency of iPSC generation from human fibroblasts, within seven days of treatment. This will provide a basis for developing safer, more efficient, non-viral methods for reprogramming human somatic cells.
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Patent Citation Ranking
- 1 Citation Count
- C12N Class
- 58.13 % this patent is cited more than
- 7 Age
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