P2X7 receptor antagonists and agonists

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United States of America Patent

PATENT NO 9908935
SERIAL NO

14403754

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Abstract

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The present invention relates to biological materials against P2X7 and more in particular to polypeptides, nucleic acids encoding such polypeptides; to methods for preparing such polypeptides; to host cells expressing or capable of expressing such polypeptides; to compositions and in particular to pharmaceutical compositions that comprise such polypeptides, for prophylactic, therapeutic or diagnostic purposes. In particular, the biological materials of the present invention inhibit the biological activity of the P2X7 receptor, such as activation by ATP.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITY MEDICAL CENTER HAMBURG-EPPENDORFMARTINISTRASSE 52 HAMBURG D-20246

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Laeremans, Toon Dworp-Beersel, BE 44 259
Nolte, Friedrich Hamburg, DE 12 8
Owusu, Danquah Welbeck Hamburg, DE 2 1
Stortelers, Catelijne Ghent, BE 35 236

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