Methods for forming protected organoboronic acids
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United States of America Patent
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Mar 6, 2018
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app pub date -
May 31, 2016
filing date -
Feb 18, 2010
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Abstract
Described are methods of forming protected boronic acids that provide in a manner that is straightforward, scalable, and cost-effective a wide variety of building blocks, such as building blocks containing complex and/or pharmaceutically important structures, and/or provide simple or complex protected organoboronic acid building blocks. A first method includes reacting an imino-di-carboxylic acid and an organoboronate salt. A second method includes reacting a N-substituted morpholine dione and an organoboronic acid.
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