Inhibitors of peptidyl arginine deiminase (PAD) enzymes and uses thereof

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United States of America Patent

PATENT NO 9908853
SERIAL NO

14418570

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Abstract

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The present application relates to imidazolidinecliones, compositions comprising these compounds and their use, in particular for the treatment of diseases, disorders or conditions characterized by or associated with the hypercitrullination of proteins by peptidyl arginine deiminase (PAD) enzymes. In particular, the present application includes compounds of Formula I, and compositions and uses thereof: (I).

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Patent Owner(s)

Patent OwnerAddress
THE HOSPITAL FOR SICK CHILDREN555 UNIVERSITY AVENUE TORONTO ONTARIO M5G 1X8

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kotra, Lakshmi Toronto, CA 6 10
Moscarello, Mario Toronto, CA 1 0

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